Gallic Acid
Medchemexpress LLC Demecolcine | 477-30-5 | 99.9% | 371.43 | 5 MG
Demecolcine is a potent mitotic inhibitor with an IC50 value of 2.4 μM for the inhibition of tubulin polymerization. Colcemid (Demecolcine) interacts with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. It can be utilized in research for inflammatory disorders and cancer.
- Potent mitotic inhibitor.
- Interacts with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth.
- Can be used for inflammatory disorders and cancer research.
- Available in solid and solution forms.
- High purity.
Medchemexpress LLC 4-fluoro-3-(4-hydroxypiperidin-1-yl)sulfonyl-N-(3,4,5-trifluorophenyl)benzamide | 1445790-55-5 | 99.9% | 432.39 g·mol-1 | C18H16F4N2O4S | 5MG
NVR 3-778 is a research-stage hepatitis B virus (HBV) capsid assembly modulator (CAM) belonging to the sulfamoylbenzamide class. It is orally bioavailable and has demonstrated antiviral activity in preclinical and clinical studies; the compound is supplied as a solid powder or as a DMSO solution for use in in vitro and in vivo research.
- Reported purity 99.88%.
- Molecular formula C18H16F4N2O4S and molecular weight 432.39 g·mol-1.
- CAS number 1445790-55-5.
- Available in small research quantities and as a 10 mM solution in DMSO.
- Used for mechanism-of-action, antiviral efficacy, and pharmacokinetic studies.
![Medchemexpress LLC Sodium 2-[[4-[[(2S)-3-methyl-1-oxo-...carbamoyl]benzoyl]amino]acetate | 144055-55-0 | 99.1% | 592.54 g/mol | C26H32F3N4NaO7 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000298375.png-250.jpg)
Medchemexpress LLC Sodium 2-[[4-[[(2S)-3-methyl-1-oxo-...carbamoyl]benzoyl]amino]acetate | 144055-55-0 | 99.1% | 592.54 g/mol | C26H32F3N4NaO7 | 10 MG
FK706 is a potent, slow-binding, competitive inhibitor of human neutrophil elastase used in biochemical and cellular research to study elastase activity and inflammation-related pathways. It is selective versus other serine proteases and has reported anti-inflammatory effects.
- Potent inhibitor of human neutrophil elastase (IC50 83 nM; Ki 4.2 nM).
- Active against mouse and porcine elastase (IC50s 22 nM and 100 nM).
- Selective versus other serine proteases such as trypsin, chymotrypsin, and cathepsin G.
- High purity (99.12%) and solid, white to off-white appearance.
- Soluble ≥100 mg/mL in water and 115 mg/mL in DMSO (sonication may be required).
- Molecular weight 592.54 g/mol; formula C26H32F3N4NaO7.
- Store sealed away from moisture; in solution: -80°C (6 months), -20°C (1 month).
Medchemexpress LLC AR420626 5mg | 1798310-55-0 | 417.29 g/mol | C21H18Cl2N2O3 | 5 MG
AR420626 is a research small molecule that functions as a selective agonist of free fatty acid receptor 3 (FFAR3/GPR41). It is used in preclinical studies to probe FFAR3-mediated signaling and biological effects, including anti-inflammatory, antidiabetic, and anticancer responses. Supplied as an off-white to light yellow solid in research-scale quantities.
- Selective FFAR3 agonist with reported nanomolar activity.
- Shown to modulate inflammatory and metabolic pathways in preclinical models.
- Available in small pack sizes suitable for in vitro and in vivo studies.
- Off-white to light yellow solid appearance for easy handling and verification.
- Recommended storage: keep powder at -20°C for long-term stability.
Medchemexpress LLC CDK12-IN-E9 10mg | 2020052-55-3 | 434.53 | C24H30N6O2 | 10 MG
CDK12-IN-E9 is a research-grade small-molecule inhibitor that selectively and covalently inhibits cyclin-dependent kinase 12 (CDK12) and non-covalently inhibits CDK9. It is supplied as a solid for use in cellular and biochemical studies of transcriptional regulation and DNA damage response.
- Potent covalent CDK12 inhibition (IC50 23.9 nM).
- Non-covalent CDK9 activity (IC50 932 nM).
- High reported purity (~99.7%).
- Molecular weight 434.53 g/mol; formula C24H30N6O2.
- Soluble in DMSO (125 mg/mL with ultrasonic).
- Available in small research pack sizes suitable for early-stage experiments.
Medchemexpress LLC Obtusifolin | 477-85-0 | 5 MG
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells by inhibiting the NF-kB pathway. It also suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein.
- Regulates MUC5AC mucin gene expression and production
- Inhibits NF-kB pathway
- Suppresses phthalate esters-induced breast cancer bone metastasis
- Targets parathyroid hormone-related protein
- Inhibits MUC5AC gene expression induced by EGF, PMA, or TNF-α in NCI-H292 cells in vitro
Medchemexpress LLC Tigulixostat | 1287766-55-5 | 99.18% | 294.31 | 50 MG
Tigulixostat (LC350189) is an orally active, non-purine selective xanthine oxidase inhibitor. It effectively reduces serum uric acid levels and is used in research for gout and hyperuricemia.
- Orally active, non-purine selective xanthine oxidase inhibitor
- Reduces serum uric acid levels
- Used in research for gout and hyperuricemia
- Solid, white to light yellow appearance
Medchemexpress LLC CDK12-IN-E9 100mg | 2020052-55-3 | 434.53 | C24H30N6O2 | 100 MG
CDK12-IN-E9 is a research-grade small-molecule inhibitor that covalently inhibits CDK12 and has non-covalent activity against CDK9. Supplied as a white to off-white solid powder, it is intended for biochemical and cellular studies of cell cycle and DNA damage pathways. Solubility and storage data support use in both in vitro and in vivo formulations.
Medchemexpress LLC Tigulixostat | 1287766-55-5 | MFCD11977724 | 95.0% | 294.31 g·mol^-1 | C16H14N4O2 | 5 MG
Tigulixostat is an orally active, non-purine selective xanthine oxidase inhibitor used in preclinical research to reduce serum uric acid in studies of gout and hyperuricemia. It is supplied as a powder and is suitable for solution preparation for biochemical and cellular assays.
- Selective xanthine oxidase inhibition with low-nanomolar potency.
- Supplied as a powder for laboratory use.
- Molecular formula C16H14N4O2; molecular weight 294.31 g·mol⁻¹.
- Pack size provided as 5 MG with solution concentration preparations noted.
- Storage: powder -20°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC Eteplirsen | 1173755-55-9 | 98.5% | 10306.00 | 50 MG
Eteplirsen (AVI 4658) is a synthetic antisense oligonucleotide for Duchenne muscular dystrophy research. It promotes dystrophin production by restoring the translational reading frame of Duchenne muscular dystrophy (DMD) through specific skipping of exon 51 in defective gene variants.
- Used for Duchenne muscular dystrophy research
- Promotes dystrophin production
- Restores translational reading frame of DMD
- Achieves specific skipping of exon 51 in defective gene variants
Medchemexpress LLC Afimetoran | 2171019-55-7 | 99.37% | 444.57 | 100 MG
Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. It inhibits TLR7/8 activation of the NF-κB pathway and can reverse TLR7-mediated resistance to steroid-induced apoptosis in plasma cell-like dendritic cells (pDCs). This compound is used for research on inflammation and autoimmune diseases, including systemic lupus erythematosus.
Medchemexpress LLC 7-oxodehydroabietic acid | 18684-55-4 | MFCD01699051 | 99.7% | 314.42 g·mol⁻1 | C20H26O3 | 5 MG
7-oxodehydroabietic acid (CAS 18684-55-4) is a diterpene resin acid used in natural product research and studies of insect endocrine-disrupting activity. It is supplied as a white to off-white solid with high reported purity for laboratory research applications.
- High purity: 99.7% as supplied on the COA.
- White to off-white solid suitable for analytical and preparative work.
- Molecular formula C20H26O3 and molecular weight 314.42 g·mol⁻1.
- Available in small milligram pack sizes for research use.
- Certificate of analysis and safety data sheet available for quality and safety verification.
Medchemexpress LLC Isotetrandrine | 477-57-6 | 5 MG
Isotetrandrine is an endogenous metabolite and a bioactive component isolated from the plant Stephania tetrandra. This alkaloid dimer is presented as a white to light yellow solid with a molecular formula of C38H42N2O6 and a molecular weight of 622.75.
- Bioactive component found in Stephania tetrandra.
- Categorized as an alkaloid and alkaloid dimer.
- Molecular formula: C38H42N2O6.
- Molecular weight: 622.75.
- Appearance: White to light yellow solid.
- Purity: ≥97.0%.
- For research use only.
Medchemexpress LLC Furobufen | 38873-55-1 | 268.26 g·mol⁻¹ | C16H12O4 | 100 MG
Furobufen is an anti-inflammatory research compound reported to produce antiarthritic and antipyretic effects and to provide analgesia in inflamed tissue. Supplied for research use only, it is documented with solubility and storage recommendations for laboratory handling.
- Has CAS number 38873-55-1.
- Chemical formula C16H12O4 and molecular weight 268.26 g·mol⁻¹.
- Supplied as a powder and may be prepared in solvent for experiments.
- Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
- Storage: powder at -20°C (stable for 3 years) or 4°C (2 years); in solvent at -80°C (2 years) or -20°C (1 year).
- Intended for research use only; not for diagnostic or therapeutic procedures.